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Cozaar (Losartan) is indicated for the treatment of hypertension.
Losartan and its primary metabolite block the angiotensin receptor found in many tissues, primarily in vascular smooth muscle. Angiotensin, formed by the action of angiotensin converting enzyme (ACE), is a powerful chemical that causes blood vessel narrowing (vasoconstriction) which can lead to elevated blood pressure (hypertension).
